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Acute cellulitis is the most common lower limb infection. The diagnosis is easy, but prompt treatment is of critical importance because of the risk of systemic or even lethal infectious complications. We analyzed the features and management of pedal cellulitis in an unselected patient population and compared these findings with the results from two other centers. All consecutive patients with a clinical diagnosis of pedal cellulitis and treated at the Department of Orthopedics, University of Tübingen and the Department of Orthopedic Surgery, University of Bonn between March 1, 2011 and March 31, 2012 were prospectively included. At the end of treatment, peripheral blood cultures were obtained and patients were transferred for follow-up (at three and six months after discharge) at the same institution. A total of 154 patients with a median age of 63 years were included in our study (female/male ratio, 1.12) and 87% of the included patients had pain. Most patients (96%) were treated with antibiotics and the most frequent antibiotic regimens were beta-lactams in combination with beta-lactamase inhibitors, which is in accordance with the current national recommendations
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